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dc.contributor.authorLozano, María C.
dc.contributor.authorRoa, Leonardo
dc.contributor.authorMoreno, Carlos A.
dc.contributor.authorVerján García, Noel
dc.contributor.authorDoncel, Benjamín
dc.date.accessioned2022-08-22T19:58:25Z
dc.date.available2022-08-22T19:58:25Z
dc.date.issued2022
dc.identifier.citationLozano, M. C., Roa, L., Moreno, C. A., Verján-García, N., & Doncel, B. (2022). Experimental intoxication of brahman (bos indicus) heifers with enterolobium cyclocarpum fruits. Toxicon, 216, 57-64. doi:10.1016/j.toxicon.2022.06.015spa
dc.identifier.issn0041-0101spa
dc.identifier.urihttps://repository.udca.edu.co/handle/11158/4822
dc.description.abstractEnterolobium cyclocarpum is a poisonous plant distributed throughout the Americas. The E. cyclocarpum fruits have high toxic potential for cattle in Colombia and the clinical signs and pathological lesions are ill-defined. To begin address this issue, twelve Brahman heifers were administered E. cyclocarpum fruits and the evolution of clinical signs were recorded. Blood was collected to establish biochemical and hematological parameters. Animals were euthanized between 4 and 15 days after the initial dose was given, and tissue samples were routinely processed and stained by Hematoxylin-Eosin. The severity of clinical signs and tissue lesions were correlated with the dose of E. cyclocarpum fruits. Clinical signs included fever, tachypnea, sialorrhea, jaundice, tympanism, and diarrhea. Skin lesions were consistent with photosensitization. Hematological and biochemical tests showed increased hematocrit, neutropenia, increased serum fibrinogen, elevated hepatic enzymes and azotemia. Histology revealed panlobular cytoplasmic vacuolization and extensive foci of necrosis in the liver. The skin, fore-stomach, abomasum and intestine revealed microcirculatory, inflammatory and ulcerative changes. Protein casts and tubular epithelium vacuolization were found in kidney. Depending on the toxicosis intensity, it is concluded that E. cyclocarpum fruits may cause two clinical and pathological forms of poisoning in Brahman heifers. First, a severe intoxication at repeated exposition with high (20 g/kg/d) or low (10 g/kg/d) dose that affected the digestive and tegumentary systems and the kidney. Second, a mild to moderate form with a single low dose (10 g/kg/d) that affected in lower grades the same systems/organs.eng
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.eseng
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourcehttps://udca.elogim.com:2119/science/article/pii/S0041010122002045?via%3Dihub#!spa
dc.titleExperimental intoxication of Brahman (Bos indicus) heifers with Enterolobium cyclocarpum fruitseng
dc.typeArtículo de revistaspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)spa
dc.description.notesIncluye referencias bibliográficas.spa
dc.identifier.doi10.1016/j.toxicon.2022.06.015
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dc.subject.agrovocEnterolobium cyclocarpum
dc.subject.agrovocPlantas tóxicas
dc.subject.agrovocGanado bovino
dc.subject.agrovocBos indicus
dc.relation.indexedAgrosaviaspa
dc.coverage.countryColombia
dc.relation.citationedition(Sep., 2022)spa
dc.relation.citationendpage8spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume216spa
dc.relation.ispartofjournalToxiconspa
dc.type.contentTextspa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa


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