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dc.contributor.authorCamargo, Milenaspa
dc.contributor.authorDel Río Ospina, Luisaspa
dc.contributor.authorSoto-De León, Sara Ceciliaspa
dc.contributor.authorSánchez, Ricardo Andreaspa
dc.contributor.authorPineda Peña, Clemenciaspa
dc.contributor.authorSussmann, Ottospa
dc.contributor.authorPatarroyo, Manuel Elkinspa
dc.contributor.authorPatarroyo, Manuel Alfonsospa
dc.identifier.citationCamargo, M., Del Río-Ospina, L., Soto-De León, S.C., Sánchez, R., Pineda-Peña, A.C., Sussmann, O., Patarroyo, M.E., Patarroyo, M.A. Association of HIV status with infection by multiple HPV types (2018) Tropical Medicine and International Health, 23 (11), pp.
dc.description.abstractObjectives: To identify the clinical and demographic characteristics of HIV-positive and HIV-negative women infected by multiple HPV types. Methods: 1399 women participated in the study (240 HIV-positive and 1159 HIV-negative women). Samples were provided for Pap tests and for HPV detection and typing by PCR. Data were collected on HPV infection, frequency of multiple infection, and HPV type distribution. Odds ratios were reported from logistic regression models. Results: Compared with HIV-negative women, HIV-positive women had higher frequencies of cervical abnormality (30% vs. 20.8%), higher HPV prevalence (68.3% vs. 51.3%) and were more commonly infected with multiple HPV types (78.7% vs. 44.3%). HPV-16 was the most common type detected in the study population, with other types showing variable associations with HIV status. Positive associations were observed between infection by multiple HPV types and HIV status, cervical abnormality and having had more than three pregnancies. The odds of multiple infection by HPV types were higher in HIV-positive women who used an intrauterine device, who had a history of abortions and who had HIV viral loads >100 000 copies/ml, whilst the odds were lower in women with >500 CD4 cells/mm 3 . Conclusions: HIV immunosuppression favours infection by multiple high-risk HPV types, mainly in women affected by low-grade squamous intraepithelial lesions. Antiretroviral therapy had no effect on infection by multiple HPV types. Risk factors related to progressive damage to the cervix were positively associated with infection by multiple HPV types in women living with HIV.eng
dc.relation.ispartofseriesTropical Medicine and International Health;Vol.23, No.11 Nov 2018 páginas 1259-1268spa
dc.rightsDerechos Reservados - Universidad de Ciencias Aplicadas y Ambientalesspa
dc.subject.meshFactores de Riesgospa
dc.subject.meshInfecciones por Papillomavirusspa
dc.titleAssociation of HIV status with infection by multiple HPV typesspa
dc.typeArtículo de revistaspa
dc.rights.creativecommonsAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)spa
dc.subject.proposalHuman immunodeficiency virusspa
dc.subject.proposalHuman papillomavirusspa
dc.subject.proposalMultiple infectionspa
dc.subject.proposalRisk factorspa

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Except where otherwise noted, this item's license is described as Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales