Now showing items 1-2 of 2

Association of HIV status with infection by multiple HPV types

Camargo, Milena; Del Río Ospina, Luisa; Soto-De León, Sara Cecilia; Sánchez, Ricardo Andrea; Pineda Peña, Clemencia; Sussmann, Otto; Patarroyo, Manuel Elkin; Patarroyo, Manuel Alfonso (2018)

Objectives: To identify the clinical and demographic characteristics of HIV-positive and HIV-negative women infected by multiple HPV types. Methods: 1399 women participated in the study (240 HIV-positive and 1159 HIV-negative ...
Behavior and abundance of Anopheles darlingi in communities living in the Colombian Amazon riverside

Prado, César Camilo; Alvarado Cabrera, Luis Antonio; Camargo Ayala, Paola Andrea; Garzón Ospina, Diego; Camargo, Milena; Soto-De León, Sara Cecilia; Cubides, Ricardo; Celis-Giraldo, Carmen Teresa; Patarroyo, Manuel Elkin; Patarroyo, Manuel Alfonso (2019)

In the past few years, relative frequencies of malaria parasite species in communities living in the Colombian Amazon riverside have changed, being Plasmodium vivax (61.4%) and Plasmodium malariae (43.8%) the most frequent. ...

Envíos recientes

Association of HIV status with infection by multiple HPV types
...
Camargo, Milena | 2018

Objectives: To identify the clinical and demographic characteristics of HIV-positive and HIV-negative women infected by multiple HPV types. Methods: 1399 women participated in the study (240 HIV-positive and 1159 HIV-negative women). Samples were provided for Pap tests and for HPV detection and typing by PCR. Data were collected on HPV infection, frequency of multiple infection, and HPV type distribution. Odds ratios were reported from logistic regression models. Results: Compared with HIV-negative women, HIV-positive women had higher frequencies of cervical abnormality (30% vs. 20.8%), higher HPV prevalence (68.3% vs. 51.3%) and were more commonly infected with multiple HPV types (78.7% vs. 44.3%). HPV-16 was the most common type detected in the study population, with other types showing variable associations with HIV status. Positive associations were observed between infection by multiple HPV types and HIV status, cervical abnormality and having had more than three pregnancies. The odds of multiple infection by HPV types were higher in HIV-positive women who used an intrauterine device, who had a history of abortions and who had HIV viral loads >100 000 copies/ml, whilst the odds were lower in women with >500 CD4 cells/mm 3 . Conclusions: HIV immunosuppression favours infection by multiple high-risk HPV types, mainly in women affected by low-grade squamous intraepithelial lesions. Antiretroviral therapy had no effect on infection by multiple HPV types. Risk factors related to progressive damage to the cervix were positively associated with infection by multiple HPV types in women living with HIV.

LEER
Behavior and abundance of Anopheles darlingi in communities living in the Colombian Amazon riverside
...
Prado, César Camilo | 2019

In the past few years, relative frequencies of malaria parasite species in communities living in the Colombian Amazon riverside have changed, being Plasmodium vivax (61.4%) and Plasmodium malariae (43.8%) the most frequent. Given this epidemiological scenario, it is important to determine the species of anophelines involved in these parasites’ transmission. This study was carried out in June 2016 in two indigenous communities living close to the tributaries of the Amazon River using protected human bait. The results of this study showed a total abundance of 1,085 mosquitos, of which 99.2% corresponded to Anopheles darlingi. Additionally, only two anopheline species were found, showing low diversity in the study areas. Molecular confirmation of some individuals was then followed by evolutionary analysis by using the COI gene. Nested PCR was used for identifying the three Plasmodium species circulating in the study areas. Of the two species collected in this study, 21.0% of the An. darlingi mosquitoes were infected with P. malariae, 21.9% with P. vivax and 10.3% with Plasmodium falciparum. It exhibited exophilic and exophagic behavior in both study areas, having marked differences regarding its abundance in each community (Tipisca first sampling 49.4%, Tipisca second sampling 39.6% and Doce de Octubre 10.9%). Interestingly, An. mattogrossensis infected by P. vivax was found for the first time in Colombia (in 50% of the four females collected). Analysis of An. darlingi COI gene diversity indicated a single population maintaining a high gene flow between the study areas. The An. darlingi behavior pattern found in both communities represents a risk factor for the region’s inhabitants living/working near these sites. This highlights the need for vector control efforts such as the use of personal repellents and insecticides for use on cattle, which must be made available in order to reduce this Anopheline’s abundance.

LEER

‹›

Browsing by Author "Soto-De León, Sara Cecilia"

Association of HIV status with infection by multiple HPV types ﻿

Behavior and abundance of Anopheles darlingi in communities living in the Colombian Amazon riverside ﻿

Envíos recientes

Association of HIV status with infection by multiple HPV types

Behavior and abundance of Anopheles darlingi in communities living in the Colombian Amazon riverside

Association of HIV status with infection by multiple HPV types

Behavior and abundance of Anopheles darlingi in communities living in the Colombian Amazon riverside