Listar por autor "Whitted, Crystal"
Mostrando ítems 1-3 de 3
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Achyrocline B (3,5 dihydroxy-6,7,8-trimethoxyflavone) synergizes with 5-fluorouracil allowing for dose reduction and reduced off-target toxicity in the treatment of colonic and pancreatic cancers
Cartwright, Brian M.; Corso, Jaclyn N.; Lightner, James; Whitted, Crystal; Torrenegra G., Ruben Dario; Koyamangalath, Krishnan; Palau, Victoria E. (2023)Surgically unresectable colorectal and pancreatic carcinomas have a high rate of mortality as current therapeutic options are limited. One common chemotherapeutic used to broadly treat both cancers is 5-flurouracil (5-Fu); ... -
Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status
LeJeune, Timothy M.; Tsui, Hei Yin; Parsons, Laura B.; Miller, Gerald E.; Whitted, Crystal; Kayla E., Lynch; Ramsauer, Robert E. (2015-11)Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted ... -
Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status
LeJeume, Timothy M.; Tsui, Hei Yin; Parsons, Laura B.; Miller, Gerald E.; Whitted, Crystal; Lynch, Kayla E.; Ramsauer, Robert E. (2015)Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted ...