Listar por autor "Patarroyo, Manuel A."
Mostrando ítems 9-17 de 17
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Plasmodium vivax in vitro continuous culture: The spoke in the wheel
Bermúdez, Maritza; Moreno Pérez, Darwin Andrés; Arévalo Pinzón, Gabriela; Curtidor, Hernando; Patarroyo, Manuel A. (2018)Understanding the life cycle of Plasmodium vivax is fundamental for developing strategies aimed at controlling and eliminating this parasitic species. Although advances in omic sciences and high-throughput techniques in ... -
Plasmodium vivax Pv12 B-cell epitopes and HLA-DRβ1-dependent T-cell epitopes in vitro antigenicity
Yepes Pérez, Yoelis; López, Carolina; Suárez, Carlos F.; Patarroyo, Manuel A. (2018)Malaria is an infectious disease caused by parasites from the genus Plasmodium (P. falciparum and P. vivax are responsible for 90% of all clinical cases); it is widely distributed throughout the world’s tropical and ... -
Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model
Lambraño, Jennifer; Curtidor, Hernando; Avendaño, Catalina; Díaz Arévalo, Diana; Roa, Leonardo; Vanegas, Magnolia; Patarroyo, Manuel Elkin; Patarroyo, Manuel A. (2019)Malaria continues being a high-impact disease regarding public health worldwide; the WHO report for malaria in 2018 estimated that 219 million cases occurred in 2017, mostly caused by the parasite Plasmodium falciparum. ... -
Shorter antibacterial peptide having high selectivity for e. Coli membranes and low potential for inducing resistance
Barreto Santamaría, Adriana; Rivera Monroy, Zuly Jenny; García Castañeda, Javier Eduardo; Curtidor, Hernando; Patarroyo, Manuel Elkin; Patarroyo, Manuel A.; Arevalo Pinzon, Gabriela (2020)Antimicrobial peptides (AMPs) have been recognised as a significant therapeutic option for mitigating resistant microbial infections. It has been found recently that Plasmodium falciparum-derived, 20 residue long, peptide ... -
Specific β-turns precede PPIIL structures binding to allele-specific HLA-DRβ1* PBRs in fully-protective malaria vaccine components
Bermudez, Adriana; Alba, Martha p.; Vanegas, Magnolia; Patarroyo, Manuel A.; Patarroyo, Manuel Elkin (2018)The 3D structural analysis of 62 peptides derived from highly pathogenic Plasmodium falciparum malaria parasite proteins involved in host cell invasion led to finding a striking association between particular β-turn types ... -
Strong -LAMP Assay Based on a Strongyloides spp.-Derived Partial Sequence in the 18S rRNA as Potential Biomarker for Strongyloidiasis Diagnosis in Human Urine Samples
Fernández Soto, Pedro; Celis Giraldo, Carmen Teresa; Collar Fernandez, Coralina; Gorgojo, Óscar; Camargo, Milena; Muñoz, José; Salas Coronas, Joaquín; Patarroyo, Manuel A.; Muro, Antonio (2020)Human strongyloidiasis a soil-transmitted infection caused by Strongyloides stercoralis is one of the most neglected amongst the so-called Neglected Tropical Diseases (NTDs). S. stercoralis is a nematode, which is distributed ... -
TCR-contacting residues orientation and HLA-DRβ* binding preference determine long-lasting protective immunity against malaria
Alba, Martha P.; Suarez, Carlos F.; Varela, Yahson; Patarroyo, Manuel A.; Bermudez, Adriana; Patarroyo, Manuel Elkin (2016)Fully-protective, long-lasting, immunological (FPLLI) memory against Plasmodium falciparum malaria regarding immune protection-inducing protein structures (IMPIPS) vaccinated into monkeys previously challenged and re-challenged ... -
The in vitro antigenicity of Plasmodium vivax rhoptry neck protein 2 (PvRON2) B- and T-epitopes selected by HLA-DRB1 binding profile
López, Carolina; Yepes Pérez, Yoelis; Díaz Arévalo, Diana; Patarroyo, Manuel A.; Patarroyo, Manuel-Elkin (2018)Malaria caused by Plasmodium vivax is a neglected disease which is responsible for the highest morbidity in both Americas and Asia. Despite continuous public health efforts to prevent malarial infection, an effective ... -
What Is Known about the Immune Response Induced by Plasmodium vivax Malaria Vaccine Candidates?
López, Carolina; Yepes Pérez, Yoelis; Hincapie Escobar, Natalia; Díaz-Arévalo, Diana; Patarroyo, Manuel A. (2017)Malaria caused by Plasmodium vivax continues being one of the most important infectious diseases around the world; P. vivax is the second most prevalent species and has the greatest geographic distribution. Developing an ...