Reacciones adversas con Levonorgestrel reportados a nivel muncial entre los años 1974-2019
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Pinto Castañeda, Aura Liliana | 2019
Emergency contraception is a method provided to women to prevent unwanted pregnancies, after having unprotected sex, or in case the planning method fails. The risks to which women who consume this medicine and the adverse reactions that may occur after consumption should be taken into account; It is important to inform women that Levonorgestrel should be used as an emergency contraceptive only twice a year according to the WHO recommendation. With 55.41%, the ages of the women who consume levonorgestrel are between 18 and 44 years old, which corresponds to the reproductive age of women, as for women who consume 45-64 years they use it as therapy for Hormonal replacement due to menopause. Combined oral contraceptives cause thrombovenous disease in women, the incidence of this disease increases with smokers, this disease causes the annual death of 370,000 women between 20 and 24 years. As for fetal deaths, they occur because consuming levonorgestrel during pregnancy does not allow the complete formation of the organs of the fetus, especially the organs of the circulatory system, for this reason there are also risks of congenital anomalies due to the consumption of levonorgestrel. As for the increase in reports generated over the years, this increased when the medication became over-the-counter because it is not possible to control its consumption. Adverse reactions caused by medical devices releasing levonorgestrel are categorized as therapeutic failures because the amount of active ingredient necessary to obtain the therapeutic effect is delivered. Common adverse reactions such as bleeding, vomiting, headaches are caused by the increase in serum hormone levels.
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